McGill University researchers have developed an artificial intelligence tool that can identify small groups of cells most responsible for driving aggressive cancers.

The tool, called SIDISH, offers scientists a clearer path to designing targeted therapies by showing which cells inside a tumour are most strongly linked with poor patient outcomes, rather than treating all cancer cells as if they behave the same way.

Stress influences what we learn and remember. The hormone cortisol, which is released during stressful situations, can make emotional memories in particular stronger. But how exactly does cortisol help the brain build emotional memories?

In a new study, Yale researchers investigated just that. Specifically, they wanted to know how cortisol acts separately on brain circuits that track emotion and those that track memory. They found that cortisol not only helped people remember emotional experiences but also enhanced emotional memory by changing the dynamic brain networks associated with both memory and emotion.

“We all experience stress, and my lab is interested in understanding how stress can be helpful,” said corresponding author Elizabeth Goldfarb, an assistant professor of psychiatry at Yale School of Medicine and of psychology in the Faculty of Arts and Sciences.

The findings are published in the journal Science Advances.