The development of treatment resistance is one of the key challenges in modern cancer and antibiotic therapy. New therapeutic approaches aim to curb the spread of resistance through the targeted timing of treatment cycles. Researchers at the Max-Planck-Zentrum für Physik und Medizin (MPZPM) have now demonstrated how a deeper understanding of the physical processes occurring in growing tumors and microbial biofilms can contribute to the success of “evolution-based” therapies.

Wiley announces the launch of two new journals, Advanced Medicine and Advanced Healthy Aging, the latest additions to its expanding Advanced Portfolio.

A systematic review and meta-analysis of 14 studies involving 7,663 patients reveals that 40% of people with chronic pancreatitis (CP) develop exocrine pancreatic insufficiency (EPI). Smoking is identified as a significant risk factor, while diagnostic method strongly influences prevalence estimates—underscoring the urgent need for standardized EPI screening and early intervention.

Wearable neuromorphic devices could enable low-power sensing and health-monitoring technologies, but many existing architectures rely on external power sources. Researchers have developed a flexible, self-powered neuromorphic device that combines a triboelectric nanogenerator with an ion-gel-gated transistor to convert mechanical movement into electrical spikes that regulate synaptic behavior. The device reproduces hierarchical memory and spike-rate-dependent learning, highlighting its potential for future wearable neuromorphic applications.

A review traces One Health from historical disease-control lessons to today’s interconnected threats and proposes an “interface-resilience” model. The model links spillover pressure, microbial community stability and governance connectivity to systemic health risk, offering a framework for earlier warning, cross-sector surveillance and preventive, data-driven health governance.

Researchers found that a polyphenol-rich Cistus salviifolius extract was particularly active against dermatophytes, including Trichophyton rubrum and Microsporum canis. Published in Journal of Ethnopharmacology, the study also found reduced fungal load and tissue invasion in a human epidermis model, supporting further research into controlled topical formulations.