Johns Hopkins Medicine leads up to $52 million federal effort to study protein shapes and folding
Grant and Award Announcement
Updates every hour. Last Updated: 21-Oct-2026 02:17 ET (21-Oct-2026 06:17 GMT/UTC)
A Johns Hopkins Medicine-led research team has received an award of up to $52.1 million over four years from the Advanced Research Projects Agency for Health (ARPA-H), part of the Department of Health and Human Services, to better understand the rules that decide what shape a protein takes — and how those rules could support the identification of earlier diagnostics and therapeutic targets when proteins fold the wrong way. The team will start this work, which will be publicly shared through open-access resources, by studying Parkinson’s disease and Ewing sarcoma, a rare cancer of bone and soft tissue in children and young adults.
Improving X-ray imaging under photon-starved conditions could enable lower-dose and higher-resolution imaging for medical diagnosis, security inspection, and industrial testing. Researchers from Chongqing University, the 26th Institute of CETC, and Stevens Institute of Technology developed a scalable photonic crystal scintillator using Marangoni effect-driven interfacial self-assembly. The approach increased average light output by 4.64-fold and improved the X-ray imaging signal-to-noise ratio by 13 dB while maintaining spatial resolution better than 25 μm.
Training doctors in rural and remote communities and embedding First Nations knowledge and leadership in medical education could be key to improving healthcare access and workforce sustainability in Australia, the United States and other underserved communities worldwide.
A new review in Infectious Diseases & Immunity brings together the evidence on how hantavirus infection affects the mouth and saliva. A severe sore throat lasting 2 to 3 weeks can be an early sign; very low platelet counts raise the risk of oral bleeding, and saliva shows promise as a non-invasive testing sample. For Andes virus, the only hantavirus known to spread between people, infectious virus has been recovered from saliva and gum fluid, so dental teams in endemic regions, and those seeing returning travelers, should know the signs and take sensible precautions.
While doctors fight to save the lives of cancer patients in intensive care, family members, partners and friends are often left carrying a heavy burden of their own, with research revealing widespread anxiety, depression, exhaustion and declining wellbeing among those supporting a loved one through a critical illness.
Four in five parents say it costs too much to have a baby, according to the University of Michigan Health C.S. Mott Children’s Hospital National Poll on Children’s Health.
ViVac Pharma has been named the winner of the 2026 Asper Prize for “The Hebrew University Rising Startup,” receiving the competition’s top honor and a NIS 100,000 award. Led by ASPER-HUJI Innovate in partnership with the Asper Foundation, the annual competition celebrates outstanding startups emerging from the Hebrew University community and highlights the University’s growing role in advancing entrepreneurship, innovation, and real-world impact.