Medicine & Health
Updates every hour. Last Updated: 2-Nov-2025 20:11 ET (3-Nov-2025 01:11 GMT/UTC)
From cellular balance to clinical breakthroughs: a comprehensive review of ROS homeostasis
Sichuan International Medical Exchange and Promotion AssociationPeer-Reviewed Publication
A recent review article published in Molecular Biomedicine highlights that a comprehensive understanding of reactive oxygen species (ROS) homeostasis is opening new avenues for therapeutic innovation. The review begins with the core principles and molecular mechanisms that govern ROS generation, scavenging, and organelle crosstalk, and then systematically elaborates how ROS dynamics influence cellular metabolism, growth, differentiation, and programmed cell death. It critically assesses how disruption of ROS homeostasis contributes to the pathogenesis of diverse diseases across the lifespan and synthesizes current and emerging strategies for modulating ROS levels. Emphasizing the need to resolve challenges of specificity and context-dependence, the authors call for the development of precise biomarkers and the exploration of combination approaches—such as pairing ROS modulators with immunotherapy or metabolic agents—to enhance efficacy. By framing ROS as both indispensable signaling mediators and potential toxins, the review argues that targeted modulation of ROS homeostasis could reshape future precision medicine, while urging more translational studies to validate and optimize these strategies for clinical use.
- Journal
- Molecular Biomedicine
Novel artificial muscles move with sound
ETH ZurichPeer-Reviewed Publication
- Journal
- Nature
Broad-spectrum virus elimination by nasal mucosa-colonized wild-type Bacillus subtilis
ResearchA research team at Nanjing Agricultural University has identified a wild-type strain of Bacillus subtilis (NS12) isolated from the nasal mucosa of outdoor pigs, which demonstrates remarkable ability to colonize mucosal surfaces and directly block viral infections.
- Journal
- Research
- Funder
- National Key Research and Development Program of China, National Natural Science Foundation of China, Natural Science Foundation of Jiangsu Province, Fundamental Research Funds for the Central Universities, China Postdoctoral Science Foundation funded project, Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
World’s leading medical journal details the climate emergency
University of SydneyPeer-Reviewed Publication
New global findings in the 2025 Lancet Countdown on Health and Climate Change reveal that the continued overreliance on fossil fuels and failure to adapt to climate change continues to be paid in people’s lives, health, and livelihoods, with 13 of 20 indictors tracking health threats now reaching unprecedented levels.
- Journal
- The Lancet
- Funder
- Wellcome Trust
GLP-1 drugs effective for weight loss, but more independent studies needed
CochranePeer-Reviewed Publication
Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions. The reviews were commissioned by the World Health Organization (WHO) to inform upcoming guidelines on the use of these drugs to treat obesity.
- Journal
- Cochrane Database of Systematic Reviews
University hospitals research published in New England Journal of Medicine shows durability of limb salvage therapy for no-option amputation patients
University Hospitals Cleveland Medical Center- Journal
- New England Journal of Medicine