Tiny tumor-triggered patches turn immune cells into cancer fighters
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Oct-2026 00:17 ET (25-Oct-2026 04:17 GMT/UTC)
Scientists from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and St. Jude Children’s Research Hospital in the United States have discovered how blood cells release an important signalling fat called sphingosine-1-phosphate, or S1P, into the bloodstream.
Researchers at the University of Osaka discovered FoeAB, a previously unknown bacterial pump that exports the antibiotic fosfomycin. By combining transport experiments with cryo-electron microscopy, the team revealed how the protein recognizes and moves the drug across the cell membrane. The findings expand understanding of antibiotic efflux in Gram-positive bacteria and could support new strategies to counter drug resistance and improve treatment of bacterial infections.
Teenagers who come from households with a lower income and lower level of education are more likely to have an eating disorder, finds a new study co-led by UCL researchers.
- A joint research team of KAIST, Seoul St. Mary's Hospital, and Konyang University College of Medicine identifies how an active vitamin A metabolite suppresses "terminal exhaustion" in cancer-attacking CD8⁺ T cells
- Activates T cells' "function-preserving switch" to sustain anti-cancer function even during prolonged combat with cancer.
- In mouse glioma models, combination with anti-PD-1 immunotherapy — which releases the 'brake' cancer cells impose on immune cells — enhances treatment efficacy and points to the potential to suppress recurrent brain tumors