A project led by the Germans Trias i Pujol University Hospital and Research Institute has developed an AI-based facial recognition system, AcroFace, capable of detecting early signs of acromegaly with 93% accuracy. The researchers are now conducting a larger pilot study with 4,000 images from the general population to confirm these promising results and improve early diagnosis of this rare disease.

Numerous studies have consistently demonstrated that a considerable proportion of patients with major depressive disorder (MDD) frequently exhibit pronounced dyslipidaemia. However, the causal dynamics between MDD and dyslipidaemia remain elusive. To comprehensively disentangle the genetic causality between MDD and various phenotypes of blood lipids, thereby facilitating the advancement of management strategies for these conditions.

A recent review article published in Molecular Biomedicine highlights that a comprehensive understanding of reactive oxygen species (ROS) homeostasis is opening new avenues for therapeutic innovation. The review begins with the core principles and molecular mechanisms that govern ROS generation, scavenging, and organelle crosstalk, and then systematically elaborates how ROS dynamics influence cellular metabolism, growth, differentiation, and programmed cell death. It critically assesses how disruption of ROS homeostasis contributes to the pathogenesis of diverse diseases across the lifespan and synthesizes current and emerging strategies for modulating ROS levels. Emphasizing the need to resolve challenges of specificity and context-dependence, the authors call for the development of precise biomarkers and the exploration of combination approaches—such as pairing ROS modulators with immunotherapy or metabolic agents—to enhance efficacy. By framing ROS as both indispensable signaling mediators and potential toxins, the review argues that targeted modulation of ROS homeostasis could reshape future precision medicine, while urging more translational studies to validate and optimize these strategies for clinical use.

Innovative artificial muscles made from silicone and equipped with microbubbles can achieve programmable deformation in response to wireless ultrasound activation. Researchers at ETH Zurich have demonstrated an array of potential applications, from a gripper arm to stingray-inspired robots and tissue patches for use as drug delivery systems. While these uses remain limited to laboratory trials for the time being, the technology has potential uses in robotics and medicine.