'Exploitative' online money gaming in India causing financial, health and social harm, analysis shows
Peer-Reviewed Publication
Updates every hour. Last Updated: 28-Nov-2025 07:11 ET (28-Nov-2025 12:11 GMT/UTC)
“Exploitative” online money gaming in India is harming people’s financial and mental health and causing deep social problems, a new study shows.
Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have discovered that this single inherited mutation causes whole-body issues in an animal model after its immune response is sparked into action.
Although the scientists stress the research is at a relatively early stage, it is one of the first pieces of work to show that a heritable mitochondrial DNA mutation can independently remodel immune cell function and inflammatory signalling.
It thus offers a plausible hypothesis as to why individuals with inherited primary mitochondrial disorders often experience problems with multiple organs and suffer repeated infections and sepsis. Additionally, it puts a potential target on specific links in the immune response chain that offer the greatest potential for therapeutic success.
A new evidence brief, based on a study by the Juno Evidence Alliance conducted in collaboration with CABI’s One Health Hub, has highlighted that a One Health approach is needed in research into zoonotic disease risks around the world.