Cornelia de Lange syndrome (CdLS) is a developmental genetic disorder. The characteristics of CdLS remain unexplored in the Chinese population. Now, a group of researchers from the National Center for Children’s Health, China, have examined the clinical presentations, mutational profiles, and hormonal therapy responses of Chinese children with CdLS. Mutations in three genes, correlation between mutations in a development-related gene and clinical presentations, and differential responses to hormone therapy were identified in Chinese patients.

Tactile sensors are indispensable in robotics, prosthetics, wearables, and healthcare monitoring. Now, researchers from SeoulTech have investigated 3D-printed auxetic metamaterials with negative Poisson's ratio behavior that enhance tactile sensor performance through inward contraction and localized strain concentration under compression. The research demonstrates superior sensitivity in both capacitive and resistive sensor configurations, with practical applications in pressure mapping arrays and wearable gait monitoring systems.