Identification of the central pathological substrate of bipolar disorder as paraventricular thalamic nucleus
Peer-Reviewed Publication
Updates every hour. Last Updated: 18-Jun-2026 16:16 ET (18-Jun-2026 20:16 GMT/UTC)
Bipolar disorder is a significant global health issue, affecting millions worldwide. To address the urgent need for novel therapeutic approaches, it is important to deepen the understanding of its pathology. A group of researchers from the Juntendo University has demonstrated how alterations and abnormalities in the neurons of the paraventricular thalamic nucleus region of the brain are associated with bipolar disorder, offering a novel therapeutic and diagnostic approach.
Five new projects for the development of innovative health technologies have been funded by the European Research Council (ERC) at the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) at its sites in Milan, Genoa and Naples. The announcement made today by the European body includes, among the 136 winners across Europe: Annamaria Petrozza and Mario Caironi in Milan, Alessandra Sciutti and Giuseppe Vicidomini in Genoa, and Velia Siciliano in Naples. The three female researchers and the two male researchers at IIT will receive Proof of Concept (PoC) grants of approximately €150,000 each, which will allow them to explore the commercial potential of their research. The fields of application include cancer, dyslexia and diagnostics.
As an emerging branch of clinical medicine, microbiota medicine has attracted worldwide attention from clinicians, medical educators, patient communities, and industry. However, this developing field still lacks consensus on its fundamental principles as well as guidelines for clinical and educational practice. An expert panel was convened by the journal Microbiota Medicine Research at the 2025 CHINAGUT Conference to develop the principles and practice guidelines of microbiota medicine.
As an emerging branch of clinical medicine, microbiota medicine has attracted worldwide attention from clinicians, medical educators, patient communities, and industry. However, this developing field still lacks consensus on its fundamental principles as well as guidelines for clinical and educational practice. An expert panel was convened by the journal Microbiota Medicine Research at the 2025 CHINAGUT Conference to develop the principles and practice guidelines of microbiota medicine.