Mass General Brigham–developed cholera vaccine completes phase 1 trial
Peer-Reviewed Publication
Updates every hour. Last Updated: 10-Jun-2026 19:15 ET (10-Jun-2026 23:15 GMT/UTC)
A team of scientists and physicians at Mass General Brigham has developed a single-dose oral cholera vaccine and tested it in a phase 1 clinical trial, with results published in The Lancet Infectious Diseases.
A new study from UCLA Health has found that long-term residential exposure to the pesticide chlorpyrifos is associated with more than a 2.5-fold increased risk of developing Parkinson's disease. The research, published in the journal Molecular Neurodegeneration, combines human population data with laboratory experiments showing how the pesticide damages dopamine-producing brain cells, providing biological evidence for the link.
The American Society of Gene & Cell Therapy (ASGCT), the leading professional organization for the advancement of cell and gene therapies (CGTs), and the Orphan Therapeutics Accelerator (OTXL), a non-profit biotech focused on completing development and enabling access to stalled rare disease treatments, today announced a partnership to establish CGTxchange, a jointly owned entity that will serve as a clearinghouse and marketplace for deprioritized CGTs.
American College of Cardiology President Christopher M. Kramer, MD, FACC, issued the following statement on the release of new Dietary Guidelines for Americans by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture.
Research from the University of Chicago shows that increases in evictions are associated with higher rates of gun violence and disrupt social cohesion in neighborhoods.
Transverse tubules (T-tubules) play significant role in muscle contraction. However, the underlying mechanism of their formation is yet to be elucidated. In a recent study, a research team from Japan used a Drosophila model to understand this process. The results show the involvement of LUBEL, an E3 ubiquitin ligase, in the T-tubule biogenesis. Beyond LUBEL’s role in immune response, the study reveals an unexpected function of linear ubiquitination in membrane deformation, driven by BAR-domain proteins.
A groundbreaking international intervention co- led by the University of Pennsylvania School of Nursing’s Center for Health Outcomes and Policy Research (CHOPR) and the KU Leuven Institute of Healthcare Policy in Belgium shows that redesigning hospital work environments with the Magnet Model® measurably improves nurse and physician wellbeing and strengthens patient safety.