Research reveals new functions of two proteins for cell function and renewal
Peer-Reviewed Publication
Updates every hour. Last Updated: 19-May-2026 09:16 ET (19-May-2026 13:16 GMT/UTC)
Middle-aged Australians are keeping the country running - but it’s taking a hefty toll on their wellbeing, a new report shows.
A new meta-analysis led by researchers in Japan investigates whether lithium (LIT) supplementation can slow cognitive decline in individuals with mild cognitive impairment (MCI) or Alzheimer’s disease (AD). Building on preclinical evidence of LIT’s neuroprotective effects, the study systematically evaluates data from six randomized controlled trials to clarify its clinical potential. The findings aim to shed light on whether LIT, long used in psychiatry, could play a future role in MCI or AD prevention or treatment.
Cannabis smoke and processed-food diets weaken the immune system, making it harder for the body to repair heart damage caused by inhaled cannabis. Cannabis compounds rapidly accumulate in major organs, including the heart, lungs and brain, where they can intensify inflammation. The risks are greatest for individuals already eating seed-oil–rich processed foods, a pattern common among populations with high rates of obesity and chronic illness.
New clinical trial results presented by TB Alliance at the Union World Conference on Lung Health show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as “SPaL.”
The NC-009 trial (a pan-Phase 2 clinical trial) showed that, overall, sorfequiline had greater activity than bedaquiline. The 100 mg SPaL regimen had greater activity against TB than the standard of care HRZE (isoniazid, rifampin, pyrazinamide, and ethambutol), indicating the potential to shorten treatment time for active TB. In addition, the SPaL regimen had a comparable safety profile to the standard of care for people with drug-sensitive TB (DS-TB).