Lack of childhood friendships linked to suicidal thoughts in over-50s.An international University of Helsinki study has found that adverse childhood circumstances increase the risk of suicidal ideation in later life.

Published in the journal Frontiers in Psychiatry, the study used AI algorithms to explore the long-term effects of early-life adversities on later mental health. The machine learning algorithms employed in the study covered over 46,000 individuals aged 50 or above and living in Europe and Israel.

Atopic dermatitis, a common chronic inflammatory skin disease, has an unclear etiology and may involve multiple factors such as genetic predisposition, immune abnormalities, and impaired skin barrier function. Currently, there is no specific medication available for the complete cure of atopic dermatitis. The current treatment approaches mainly focus on symptom relief and control rather than curative treatment. Some commonly used medications for atopic dermatitis, such as topical corticosteroids and immunosuppressants, may have certain adverse reactions and side effects. This review summarizes the research progress on natural extracts in the treatment of atopic dermatitis, aiming to provide a foundation for the development of safe and side-effect-free medications.