How citrullination of CAMP contributes to IBD: A new mechanism of immune dysfunction
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Updates every hour. Last Updated: 22-May-2026 03:16 ET (22-May-2026 07:16 GMT/UTC)
In the decades following deinstitutionalization, the U.S. has yet to find an effective model of a comprehensive behavioral health continuum of care, from prevention to intervention, treatment and recovery. Federal Certified Community Behavioral Health Clinics (CCBHC) have grown to be the dominant model for comprehensive community mental health services across the country since 2014. However, the mechanisms of federal policies and funding resulted in implementation of CCBHCs that is not consistent across all parts of the country, with large variations between states. Massachusetts’ Community Behavioral Health Centers (CBHC) is similar to the federal model and was launched in 2023.
In a new study in the journal Frontiers in Health Services, researchers from Boston University Chobanian & Avedisian School of Medicine compared the Massachusetts and federal models and found that these programs share a similar policy backbone and intention, such as a comprehensive outpatient clinic, 24/7 crisis services, bundled payments and quality incentives, but differ in important details like how they’re paid, who regulates them and how specific crisis services are structured.
Fewer than 1 in 4 children aged 2 to 4 meet the recommended daily physical activity levels, a new study has found. Additionally, while children are much more active on days when they attend early years settings, most preschoolers are not meeting the recommended activity levels within early years settings or at home.
Researchers at Yale University have identified cytosolic phospholipase A2 (cPLA2) as a key driver of cartilage degeneration and chondrocyte senescence in osteoarthritis and intervertebral disc degeneration. Through genetic deletion and pharmacological inhibition using fexofenadine, they effectively suppressed inflammation, preserved cartilage integrity, and alleviated pain in preclinical models. The study positions cPLA2 as a promising therapeutic target and highlights fexofenadine, a widely available, FDA-approved drug, as a potential repurposed treatment for debilitating musculoskeletal disorders.
Scientists have engineered a nanowire platform that mimics brain tissue to study astrocytes, the star-shaped cells critical for brain health, for the first time in their natural state.