As a highly differentiated sensory organ, the maintenance of the eye's physiological functions relies on rigorous metabolic regulation. The Tricarboxylic Acid (TCA) cycle within mitochondria serves as the core pathway for ocular energy metabolism, providing essential metabolic substrates and reducing equivalents for corneal homeostasis and retinal phototransduction. However, a critical scientific question remains: is there significant heterogeneity in energy utilization across different anatomical tissues of the eye? Furthermore, how does biological sex regulate the ocular metabolic profile through distinct biological pathways?  A study recently published in Eye Discovery (2026) utilized high-sensitivity Liquid Chromatography-Mass Spectrometry (LC-MS) to achieve absolute quantification of TCA cycle intermediates in mouse ocular tissues. Conducted by a team from West Virginia University, the research aims to construct a standardized ocular metabolic reference model, revealing dual differences in metabolic characteristics based on spatial distribution and biological sex.

Scientists from the Max Planck Institute for Marine Microbiology discover that a group of beneficial gut bacteria and their marine relatives use the same feeding strategies. This sheds new light on the potential of these bacteria for gut health research, as well as their role in marine carbon cycling.

At 11 AM on April 2, Korea University's College of Medicine (Dean Pyun Sung-bom) and Armed Forces Capital Hospital (Director Seok Woong) signed an MOU in the Korea University College of Medicine Main Building Conference Room for the development of public health and medical care, as well as the enhancement of medical training.

Researchers at Washington University School of Medicine in St. Louis have identified a previously unknown biological process that helps explain why only a subset of patients with alpha1-antitrypsin deficiency develop liver disease.