Chonnam National University study explores therapeutic potential of human dental pulp stem cell secretome in post-stroke functional recovery
Peer-Reviewed Publication
Updates every hour. Last Updated: 21-Oct-2026 21:17 ET (22-Oct-2026 01:17 GMT/UTC)
The human dental pulp stem cell (hDPSC) secretome, enriched in neurotrophic, antioxidant, and immunomodulatory factors, shows strong therapeutic promise. A new study suggests that the hDPSC secretome may support functional recovery after ischemic stroke. In cell and animal models, treatment reduced oxidative stress, neuroinflammation, and neuronal apoptosis while promoting neurogenesis, vascular remodeling, and synaptic recovery. These molecular and structural changes were accompanied by improved motor performance, spatial learning, and memory-related behaviors.
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