Pain is an important physiological response triggered by physical injury or psychological stressors. While studies have shown that mice housed with mice experiencing pain show heightened pain sensitivity, underlying mechanisms remain unclear. A new study by researchers from Tokyo University of Science finds that exposure to stress calls emitted by mice experiencing pain triggers pain and inflammation in naïve mice, thus providing novel insights into pain perception and its social transmission.

Diabetes affects millions worldwide, causing both nerve and metabolic complications. A recent study suggests that diabetic nerve damage may also lead to impaired bone health. Using a mouse model of Type 2 Diabetes, researchers uncovered that sensory nerve loss in tissues surrounding bones disrupts key cell signaling pathways in bone tissue—leading to reduced strength and regenerative capacity. The study offers new insights on the link between neuropathy and skeletal deterioration.

Gene delivery is a key area in biomedicine, where nucleic acids are delivered into cells to treat diseases by modulating genes. The low micelle concentration, effective nucleic acid complexation, and low immunogenicity make Gemini surfactants promising gene delivery vectors. Recently, a paper published in MedComm-Future Medicine summarizes strategies to improve the transfection efficiency or biocompatibility of Gemini surfactant vectors and explores their delivery mechanisms, thereby offering new insights into the field's development.