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Medicine & Health

Updates every hour. Last Updated: 21-May-2026 03:15 ET (21-May-2026 07:15 GMT/UTC)

Stopping and restarting certain GLP-1s to lose weight may make the drug less effective

University of Pennsylvania School of Medicine
Peer-Reviewed Publication

Inconsistent use of some GLP-1 weight-loss medications may significantly lessen their effectiveness, according to a new preclinical study.

Critical Path Institute awards $456,000 grant to advance next-generation therapy for rare glycolipid storage disorders

Critical Path Institute (C-Path)
Grant and Award Announcement

Critical Path Institute® today announced a $456,000 grant to James Shayman, M.D., at the University of Michigan, to support development of a brain-penetrant therapy for glycosphingolipid storage disorders. The award is part of C-Path’s Bridging Research and Innovation in Drug Development Grants (BRIDGe) program, offered through its Translational Therapeutics Accelerator.

New study finds link between difficulty identifying emotions and higher chronic pain levels

Johns Hopkins Medicine
Peer-Reviewed Publication

A large, two-year study led by researchers at Johns Hopkins Medicine and consisting of more than 1,400 adults living with chronic pain across the United States found that people who struggle to identify and describe their emotions experience greater disruption to daily life from pain over time due to increased psychological distress.

Journal: Health Psychology
Funder: Johns Hopkins Clinician Scientist Award

Targeted therapy drug shows early promise against KRAS-driven lung and pancreatic cancers

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

A first-in-human clinical trial led by an international team of researchers and published in the New England Journal of Medicine found that setidegrasib, an investigational targeted therapy drug designed to eliminate a key cancer-driving protein called KRAS G12D, shows encouraging early activity in patients with advanced lung and pancreatic cancers.

Brain-computer interface based on Rice research wins FDA approval for first clinical trial

Rice University
Business Announcement

Motif Neurotech, a company commercializing technology based on research at Rice, has received approval from the FDA to begin the first clinical trial of its therapeutic brain-computer interface for treatment of treatment-resistant depression.

Funder: Advanced Research Projects Agency for Health

PCORI awards funding for new patient-centered healthcare research supporting better-informed decision making

Patient-Centered Outcomes Research Institute
Grant and Award Announcement

The Patient-Centered Outcomes Research Institute (PCORI) announced new funding to support patient-centered comparative clinical effectiveness research (CER) across a range of health conditions experienced by Americans, along with projects designed to help bring practice-changing CER results into real-world care settings.

New method reveals cellular makeup of environments that favor metastatic cancer growth

Baylor College of Medicine
Peer-Reviewed Publication

Researchers at Baylor College of Medicine and collaborating institutions developed a method that reveals the cellular makeup of tissues that support metastatic cancer growth, which is the primary cause of death for most patients with solid tumors. The method not only revealed cellular features shared by metastatic niches of multiple cancer models but also uncovered an unexpected driver of immune suppression in bone metastasis.

Journal: Cell

Care coordination and hospitalization in older adults with or at risk for cardiovascular disease

JAMA Network
Peer-Reviewed Publication

About The Study: In this randomized clinical trial, proactive outreach for offering care coordination in advance of hospitalization did not result in better outcomes compared with usual care offering posthospitalization coordination. Many participants declined the proactive outreach offer.

Journal: JAMA Network Open

UH professor urges better prevention and care of liver disease to reduce burden

University of Houston
Peer-Reviewed Publication

A University of Houston College of Pharmacy professor has found the staggering cost of chronic liver disease for patients in the United States reaches $41.57 billion and takes a significant toll on human life, urging stronger prevention and management efforts.

Journal: Expert Review of Pharmacoeconomics & Outcomes Research

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