Research shows that greater subjective well-being can lead to enhanced immune function and a lower incidence of chronic disease. But when does happiness start to exert its positive influence, and is there a point when this effect caps out? Researchers looked at national level data from 123 countries and found there is: on a scale from zero to 10, people started gaining health benefits once they surpassed a threshold that lies at around 2.7. Once above, each 1% of additional happiness could lead to a small decrease in mortality risk from non-communicable diseases.

The winners of the Applied Microbiology International Horizon Awards 2025 have been announced. The prizes, awarded by the learned society Applied Microbiology International (AMI), celebrate the brightest minds in the field and promote the research, group, projects, products and individuals who continue to help shape the future of applied microbiology.

The first national randomized trial of public Montessori preschool students showed stronger long-term outcomes by kindergarten, including elevated reading, memory, and executive function as compared to non-Montessori preschoolers. The research also appears highly actionable for policymakers, because the results found the Montessori programs delivered better outcomes at sharply lower costs. The study of 588 children across two dozen programs nationwide shows an imperative to follow and study these outcomes through graduation and beyond.

A new study published in The Lancet Child & Adolescent Health found that the loss of US bilateral health aid is projected to result in an additional 2.5 million pediatric TB cases and 340,000 pediatric TB deaths in LMICs between 2025 and 2034, compared to pre-2025 funding levels. Moreover, the possible withdrawal of US support to the Global Fund to Fight AIDS, Tuberculosis, and Malaria (the Global Fund) along with reduced TB funding from other countries would likely result in an additional 8.9 million child TB cases, and more than 1.5 million child deaths during this period—more than double the expected totals if funding continued at pre-2025 levels.