EurekAlert! News by Subject: Tech & Engineering - News by Subject: Tech & Engineering

Tech & Engineering

Updates every hour. Last Updated: 26-Apr-2025 02:08 ET (26-Apr-2025 06:08 GMT/UTC)

Researchers use genomic technology to investigate aggressive skin cancer linked to burn scars

University of Calgary
Peer-Reviewed Publication

University of Calgary study reveals new insights that could help in the diagnosis and treatment of invasive skin cancers, like Marjolin’s ulcer (MU), that grow on chronic burn wounds. The research team completed a cell-by-cell analysis to better understand how MU tumours grow. Using both single cell RNA sequencing and spatial transcriptomics provided precise mapping of gene expression and cellular interactions within tumor tissue sections. With that enhanced view the researchers discovered that a subset of the dermal fibroblasts residing within the tumor, appeared to have come from keratinocytes that typically comprise the outer layer of the skin called epidermis. Findings are published in the Journal of Investigative Dermatology.

Journal: Journal of Investigative Dermatology
Funder: Calgary Firefighters Burn Treatment Society

Children’s Hospital of Philadelphia researchers discover underlying mechanisms that make CRISPR an effective gene editing tool

Children's Hospital of Philadelphia
Peer-Reviewed Publication

Using state-of-the-art technology, researchers have identified several specific steps needed for CRISPR to become active and perform its gene editing function. These preclinical findings could lead to improved designs for CRISPR-based gene editing.

Journal: Cell Chemical Biology
Funder: NIH/National Institute of Allergy and Infectious Diseases, Cancer Grand Challenges, Cancer Research UK, NIH/National Cancer Institute, Mark Foundation For Cancer Research, NIH/National Institutes of Health, NIH/National Institutes of Health, Claudia Adams Barr Program for Innovative Cancer Research

Impella ECP pivotal study demonstrates safety, efficacy for use in high-risk PCI

Abiomed
Meeting Announcement

DANVERS, Mass. – October 28, 2024 – Results were presented at Transcatheter Cardiovascular Therapeutics (TCT) 2024 conference from the first completed pivotal trial on patients supported with Impella ECP™, a novel transvalvular axial flow pump with compressible pump architecture. Impella ECP is a technology of Abiomed, part of Johnson & Johnson MedTech, and the global leader in heart recovery.

Meeting: TCT 2024: Transcatheter Cardiovascular Therapeutics

SwRI adds new chamber for spacecraft-related EMC, EMI testing

Southwest Research Institute
Business Announcement

SAN ANTONIO — October 28, 2024 —Southwest Research Institute (SwRI) has added a semi-anechoic shielded enclosure for electromagnetic compatibility and interference (EMC/EMI) testing for spacecraft. The test chamber is the next step in SwRI’s plans to create a turnkey spacecraft integration and test center within its 74,000-square-foot Space System Spacecraft and Payload Processing Facility.

Mizzou scientists create geochemical fingerprints

University of Missouri-Columbia
Peer-Reviewed Publication

University of Missouri scientist Brandi L. MacDonald is using modern technology only found at Mizzou to help researchers expand the collective understanding of how human thought and intellect has developed over time.

In a recent study, an international team of scientists partnered with MacDonald to access advanced scientific technology at the University of Missouri Research Reactor (MURR), Materials Science and Engineering Institute (MSEI) and Electron Microscopy Core (EMC). Using Mizzou’s resources and expertise, the team, led by MacDonald, was able to confirm the location of the world’s oldest ochre mine and trace how ochre from the mine was dispersed to nearby communities.

Ochre is naturally occurring pigment that comes from iron-rich materials. As one of Earth’s oldest materials, it has been used by people for thousands of years. Known as a pigment for cave paintings, and decoration of symbolic objects and personal ornamentation, it holds cultural, historical and spiritual significance in many societies. Its enduring presence offers scientists valuable insights into the growth of human society and self-expression.

Journal: Nature Communications

NCCN Cancer Center study demonstrates usability of Health Equity Report Card (HERC) tool for driving fair access to care

National Comprehensive Cancer Network
Reports and Proceedings

National Comprehensive Cancer Network (NCCN) presents preliminary data from a study demonstrating the usability of the Health Equity Report Card (HERC) tool during the American Public Health Association (APHA) Annual Meeting and Expo.

Meeting: American Public Health Association Annual Meeting and Expo

Danforth Technology Company launches new startup

Donald Danforth Plant Science Center
Business Announcement

The Danforth Technology Company (DTC) today announced the launch of Metablify, a startup that has developed a breakthrough technology platform that enables the detection and quantification of previously undetectable metabolites and chemicals in large numbers of biological samples processed using LC/MS data processing algorithms.