The New Generation Ultrasound “Microscope”! A team from Nanjing University has developed an ultrafast ultrasound localization microscopy technology
Peer-Reviewed Publication
Updates every hour. Last Updated: 20-Aug-2025 22:11 ET (21-Aug-2025 02:11 GMT/UTC)
Professors Juan Tu, Dong Zhang, Jingning Zhu, and Academician Ning Gu from Nanjing University developed an ultrafast ultrasound localization microscopy algorithm combining velocity constraints and motion compensation. This breakthrough technique achieves super-resolution imaging of microvascular networks in organs like the rat brain and kidney, producing high-definition “microscopic maps of life pathways”. It provides a powerful new imaging tool for medical research and the diagnosis and treatment of cardiovascular and microcirculatory diseases. The work, titled “Velocity-Constraint Kalman Filtering for Enhanced Bubble Tracking in Motion Compensated Ultrasound Localization Microscopy”, was recently published in Research (2025, 8:0725, DOI: 10.34133/research.0725).
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