Earth-based telescopes offer a fresh look at cosmic dawn
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Jun-2025 16:10 ET (26-Jun-2025 20:10 GMT/UTC)
In a paper published on aBIOTECH, the authors constructed G protein mutants using CRISPR/cas9 technology and investigated the biological functions of G proteins in growth, development, and symbiotic nodulation in Medicago truncatula.
Dr. Hye Jin Nam’s team at the Korea Research Institute of Chemical Technology (KRICT), in collaboration with Professors Dong Hyun Jo and Sangsu Bae at Seoul National University College of Medicine, found that autophagy induction via nutrient deprivation or mTOR inhibition markedly enhances the efficiency of HR-based CRISPR–Cas9 gene editing up to threefold.
Realizing the point-of-care tumor markers biodetection with good convenience and high sensitivity possesses great significance for prompting cancer monitoring and screening in biomedical study field. Herein, the quantum dots luminescence and microfluidic biochip with machine vision algorithm-based intelligent biosensing platform have been designed and manufactured for point-of-care tumor markers diagnostics. The employed quantum dots with excellent photoluminescent performance are modified with specific antibody as the optical labeling agents for the designed sandwich structure immunoassay. The corresponding biosensing investigations of the designed biodetection platform illustrate several advantages involving high sensitivity (~ 0.021 ng mL-1), outstanding accessibility, and great integrability. Moreover, related test results of human-sourced artificial saliva samples demonstrate better detection capabilities compared with commercially utilized rapid test strips. Combining these infusive abilities, our elaborate biosensing platform is expected to exhibit potential applications for the future point-of-care tumor markers diagnostic area.
Would you trust a driverless car? A a new study by Australian and French researchers shows that augmented reality (AR) could increase overall confidence in autonomous vehicles by simulating the experience and allowing drivers to personalise the AR interface.