IEEE researchers achieve 20x signal boost in cerebral blood flow monitoring with next-generation interferometric diffusing wave spectroscopy
Peer-Reviewed Publication
Updates every hour. Last Updated: 2-Apr-2026 04:16 ET (2-Apr-2026 08:16 GMT/UTC)
Light speckle fluctuations, a noninvasive proxy for cerebral blood flow index (CBFi), are quantified by diffuse correlation spectroscopy. However, this conventional technique provides marginal brain sensitivity for CBFi in adult humans. To improve the brain sensitivity, researchers have now optimized interferometric diffusing wave spectroscopy—a novel approach to quantify the fluctuations. They demonstrated pulsatile CBFi monitoring at 4–4.5 cm source-collector separation in adults with moderate pigmentation.
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