Researchers from the Chinese Academy of Sciences and Capital Medical University performed an integrated multi-omics study to compare the effects of acute versus long-term exercise in healthy men. Acute exercise led to temporary responses, while repeated exercise caused adaptive changes, particularly reducing cellular senescence and inflammation and boosting betaine metabolism. The increase in betaine due to exercise, partly through renal biosynthesis, has anti-aging effects and improves age-related health decline in mice. Betaine binds to and inhibits TANK-binding kinase 1 (TBK1), slowing the aging process. These results provide a comprehensive understanding of the molecular benefits of exercise and identify betaine as a potential exercise mimetic for promoting healthy aging.

New research shows hot tubs may offer greater health benefits than saunas, including lower blood pressure and a stronger immune response.

25 June 2025/Kiel. Overfishing not only depletes fish stocks — it also alters the genetic blueprint of marine life. In the central Baltic Sea, cod (Gadus morhua) have not only become scarcer, but also significantly smaller than in the past. Researchers at the GEOMAR Helmholtz Centre for Ocean Research Kiel have now shown for the first time that Eastern Baltic cod grow markedly more slowly than they once did, and that this change is reflected in their genome. Intensive fishing pressure triggers genetic responses in overexploited stocks, with long-term implications for their future development. The findings are published today in the journal Science Advances.