The Korea Railroad Research Institute (KRRI) (President: Sagong Myung) conducted a field demonstration on May 13 (Wed.) at a concrete sleeper storage site near Gimyujeong Station in Chuncheon for railway industry officials and other stakeholders, showcasing the “End-of-Life Concrete Sleeper Recycling System,” which crushes, separates, and sorts waste concrete into recyclable materials such as reinforcing steel and aggregates.

SKKU InfoLab develops a 4D fMRI AI model that analyzes brain activity across space and time while providing interpretable information for trustworthy computer-aided diagnosis

A  review in the Chinese Journal of Natural Medicines provides a systematic guide to mainstream mass spectral databases and computational annotation methodologies — from GNPS and SIRIUS to molecular networking — charting the path toward discovering novel natural entities.

In contemporary practice, elevated 24-hour urinary copper excretion (24-h UCE) often triggers referral for suspected Wilson disease (WD). In this hypercupriuric referral setting, interpretation of 24-h UCE may be distorted by spectrum effects. In this study, we aimed to compare conventional copper biomarkers in hypercupriuric referrals and evaluate whether a Leipzig-aligned ceruloplasmin (Cp) framework could provide a clinically useful triage approach.

The tea industry is an important part of China’s agricultural economy, but the industrial development challenge of “who will grow tea and how to grow it well” has become increasingly prominent. In the face of realities such as accelerating aging of the rural labor force and insufficient resource endowments of smallholder farmers, promoting the implementation and widespread adoption of agricultural socialized services has become a key path to overcoming the development dilemma of the tea industry.

A  study published in Alzheimer’s Research & Therapy detects increased levels of the active form of meprin-β in advanced stages of the disease and of its messenger RNA in intermediate stages.

The researchers also observe increased levels of the protein when human neurons are exposed to beta-amyloid, pointing to a possible relationship between the two processes.

Liver fibrosis is a central process in chronic liver disease, yet effective antifibrotic therapies remain limited. The mineralocorticoid receptor (MR) is a key regulator of hepatic homeostasis and fibrogenesis, expressed in hepatocytes, hepatic stellate cells (HSCs), macrophages, and liver sinusoidal endothelial cells (LSECs). MR activation—via aldosterone‑dependent and ligand‑independent mechanisms (hypoxia, oxidative stress)—amplifies TGF‑β signalling, ROS generation, and NF‑κB‑driven inflammation, forming a self‑reinforcing fibrogenic network. Preclinical studies show MR antagonists (MRAs) attenuate fibrosis. Clinical evidence remains limited. Nonsteroidal MRAs, particularly finerenone, offer improved selectivity and safety. Future research should focus on patient stratification, validated endpoints, and rigorous safety evaluation.

PSVD is characterised by presinusoidal portal hypertension with preserved liver function. Conventional HVPG significantly underestimates true portal pressure in PSVD. This review focuses on precise portal pressure assessment, summarising advances in EUS‑guided portal pressure gradient (PPG) measurement, elastography, advanced imaging, radiomics, and AI‑assisted strategies.