A research team has identified cytosine monophosphate kinase 2 (CMPK2) as a key molecular driver of hepatic ischemia-reperfusion injury (HIRI) and shown that acteoside (ACT), a natural compound found in traditional Chinese medicinal herbs, can protect the liver by interrupting CMPK2-centered redox metabolism. 

The development of a highly responsive and selective gas sensor for volatile organic compounds, such as hydrogen sulfide and acetone, is still required. In a recent study carried out by Chen et al., FeWO₄ hollow spheres modified with Pd nanoparticles were synthesized using ammonium phosphotungstate hydrate dodecahedra as sacrificial templates followed by liquid-phase reduction.

An integrative review led by the Afrifa-Yamoah research team and co-authored by scholars from Canada, Australia and other countries has been published in Eye & ENT Research. Against the backdrop of the global myopia epidemic, this paper systematically elaborates the genetic, optical and environmental mechanisms driving the onset and progression of myopia, and analyzes the underlying principles of relevant risk factors. It also classifies mainstream myopia correction and control measures, summarizes their clinical effects, and puts forward clinical strategies for personalized and combined interventions. This study provides comprehensive and authoritative theoretical references for clinical ophthalmology practice, myopia prevention and control, as well as future research.

This report presents the first documented case of an extraosseous Ewing’s sarcoma (ES) arising primarily in the retropharyngeal space of an adult. A 59-year-old female presented with progressive dysphagia and acute stridor, initially mimicking a retropharyngeal abscess. However, intraoperative findings showed no pus, and further immunohistochemistry and genetic testing confirmed ES with CD99 positivity and EWSR1 rearrangement. Despite multimodal considerations, the disease was extensive at diagnosis, and the patient deteriorated rapidly, passing away within two months.

A recent case report from Mayo Clinic in Eye & ENT Research documents the first-ever case of vocal fold paralysis (VFP) following Z-POEM. A 68-year-old male developed hoarseness one day after the procedure, and laryngoscopy later confirmed left VFP. This finding breaks the prior safety record of Z-POEM and highlights the vulnerability of the recurrent laryngeal nerve, which lies close to the diverticulum base and is at risk during septal division. This article presents the case from anatomical, diagnostic, and management perspectives, offering a critical safety reference for clinicians performing Z-POEM.

 Researchers have uncovered the initial adaptive mechanisms of Bacillus velezensis C5 when exposed to polyethylene microplastics. Using comparative transcriptomics, the study revealed a robust, polymer‑specific transcriptional program distinct from general starvation or surface‑contact responses. Exposure to polyethylene triggered massive upregulation of genes involved in biofilm formation and sporulation, while genes associated with canonical degradation were not induced. The bacterium remained viable without growth, formed dense biofilms, and increased surface hydrophilicity but caused only subtle physicochemical changes to the plastic. This survival‑first strategy represents a critical initial phase that must be overcome to enable efficient biodegradation.

A comprehensive Cal Poly study examining North American bird population data reveals that environmental change does not affect all species equally. The research, assessing data collected across North America over nearly 30 years, found that no single environmental factor explained bird population changes across all species. Instead, species responded in highly individualized ways because of their interactions with their environment. While human-caused disturbances such as light pollution and air pollution can negatively affect bird populations, ecological traits can help predict species' sensitivity and forecast how well they will respond to ongoing environmental change. The study also highlights the importance of local conservation action. While climate change and regional air pollution require broad policy solutions, many environmental factors affecting birds can be addressed at the level of cities or counties.