On 1 August 2025, China's GBZ 337–2025 Diagnostic Standard for Occupational Post-Traumatic Stress Disorder came into force.1 For the first time, post-traumatic stress disorder (PTSD) among emergency responders, including police, firefighters and medical personnel, has been formally recognised as an occupational condition, eligible for compensation under the country's occupational injury system. This move marks a significant institutional acknowledgement that psychological trauma can be as disabling and deserving of protection as physical injury. Far from an isolated policy decision, GBZ 337–2025 marks a milestone in decades of evolving scientific understanding, public awareness and policy development, shaped by the lived experiences of natural disasters and public health emergencies in China.

Published in Engineering, this review systematically sorts interdisciplinary engineering therapies for spinal cord injury. It analyzes the three-stage secondary pathological cascade after trauma and elaborates five core intervention branches including neuromodulation, cell transplantation, and functional biomaterials. The article also identifies major translational obstacles and advocates integrated multimodal treatment plus cross-field cooperation to speed clinical transformation of SCI repair technologies.

A newly published review in Engineering defines mitochondrial deacetylase SIRT3 as the core ‘‘head goose molecule’’ triggering negentropic mechanisms to reverse diabetes, obesity, and steatotic liver disease. It sorts three classes of SIRT3 activators and notes translational hurdles, providing systematic theoretical support for targeted metabolic disease therapies.

This report features a multicenter One Health study published in Engineering, tracking apramycin-resistant Escherichia coli (AREC) across livestock chains and human populations in three Chinese cities. The transferable aac(3)-IV gene on IncHI2/IncHI2A plasmids drives cross-host resistance spread. Growing veterinary apramycin consumption lifts resistance prevalence, reminding authorities to prudently evaluate its potential human clinical application.

This study reveals a novel multi-target skin-whitening strategy using Haematococcus pluvialis extract (HPE) combined with niacinamide (NAM). By integrating B16F10 melanoma cell assays and a HaCaT/MNT-1 transwell coculture model, the study demonstrates that HPE not only suppresses melanin synthesis through tyrosinase inhibition but also reduces melanosome transfer. Moreover, HPE and NAM exhibit synergistic effects on pigmentation regulation, with combination treatments showing enhanced inhibition of melanin accumulation. These findings provide new mechanistic insights into natural bioactive ingredients and support the development of more effective, sustainable, and multifunctional whitening formulations.