This review systematically summarizes the anti-aging potential of plant-derived ingredients in skincare, emphasizing their multifunctional roles in moisturizing, barrier repair, antioxidation, photoprotection, and anti-inflammation. It highlights how bioactive compounds such as polysaccharides, polyphenols, flavonoids, and vitamins target key mechanisms of skin aging, including oxidative stress, collagen degradation, and UV-induced damage. The article also discusses the growing consumer preference for natural, safe, and sustainable cosmetics, alongside industry trends toward plant-based formulations. By integrating biological mechanisms with application strategies, this work provides valuable insights for developing effective, green, and multifunctional anti-aging cosmetic products.

A 2025 study conducted by researchers from the Ludwik Hirszfeld Institute of Immunology and Experimental Therapy PAS, Wroclaw Medical University and the University of Connecticut shows that oral health, immune function and cognitive decline are closely interconnected in Alzheimer’s disease. The findings contribute to the growing concept of the mouth–brain axis, suggesting that even mild, chronic inflammation of the gums may have systemic consequences. The study demonstrated that patients with Alzheimer’s disease not only present worse oral hygiene and increased gingival inflammation, but also exhibit significant dysregulation of the immune system, characterized by reduced baseline activity alongside an exaggerated response to bacterial stimulation. This imbalance may reflect both immune exhaustion and hyperreactivity, which together can contribute to harmful inflammatory processes. Importantly, the severity of gingival inflammation was associated with lower cognitive test scores, regardless of age or sex, indicating a direct relationship between oral health and cognitive performance. The proposed mechanism suggests that chronic periodontal inflammation places a continuous burden on the immune system, leading to its dysfunction and facilitating the penetration of inflammatory signals into the brain, where they may enhance neuroinflammation and accelerate disease progression. The study also highlights a practical challenge, as individuals with Alzheimer’s disease tend to neglect daily oral hygiene, which further exacerbates the problem. These results underline that oral health should be considered an integral part of systemic health and dementia care, and that simple preventive measures, such as maintaining proper oral hygiene and supporting patients through caregiver involvement, may have meaningful implications for brain health.

This study developed a hydrating oil-in-water (O/W) cream incorporating Echinacea extract as a natural preservative and antimicrobial agent, aiming to replace synthetic parabens commonly used in cosmetic formulations. The results demonstrated that the formulated cream exhibited excellent skin absorption and significant moisturizing capacity while maintaining desirable physicochemical stability. In antimicrobial preservative efficacy tests conducted over 28 days, the cream effectively inhibited bacterial growth, confirming the functional potential of Echinacea extract as a bioactive alternative to conventional preservatives. Moreover, under accelerated stability conditions, the formulation remained homogeneous and stable for six months without phase separation. These findings highlight the feasibility of utilizing plant-derived extracts to enhance both safety and performance in cosmetic products and provide experimental support for the development of natural, multifunctional skincare formulations.

The Hebrew University of Jerusalem and its Faculty of Medicine proudly congratulate Prof. Avraham (Avi) Rivkind on being awarded the Israel Prize in the category of Lifetime Achievement – Special Contribution to Society and the State. Prof. Rivkind, a graduate of the Faculty of Medicine and a longtime member of its academic staff, received the award in recognition of his decades-long leadership in advancing trauma care in Israel. His work includes the establishment and development of the national trauma system, as well as the trauma center at Hadassah–Ein Kerem Medical Center.