Candida auris is a rising global health threat due to multidrug resistance, emphasizing the urgent need for novel antifungal strategies. The C. auris glycosylphosphatidylinositol transamidase (GPI-T) complex is the key enzyme that mediates the attachment of GPI anchors to target proteins.

Researchers have identified a critical genetic pathway involving the protein FOXO1 that maintains the health of the epididymis, a vital component of the male reproductive system. The study reveals that the age-related decline of this pathway drives cellular senescence and infertility. Furthermore, experimental treatments using specialized stem cells demonstrated the ability to restore this pathway, offering a promising new strategy for preserving male reproductive longevity.

A new clinical study shows that electroacupuncture (EA) can significantly improve long-term facial paralysis symptoms and help regulate brainstem excitability, even when using minimal stimulation that patients can barely feel. 

Severe early childhood caries affects millions of children worldwide and remains one of the most destructive forms of tooth decay. Although bacteria are known to play a central role in the disease, identifying the microbes actively involved in lesion progression has remained a challenge. In a new study, researchers combined DNA and RNA sequencing to investigate microbial communities residing within carious lesions, offering new insights into the biological processes that drive this debilitating childhood condition.

Oral delivery platform is designed to protect therapeutic enzymes in the stomach and activate treatment selectively at tumour sites.

As shifting federal priorities, sweeping agency restructurings, and deep funding cuts continue to reshape the American public health infrastructure, a new study reveals the staggering toll these disruptions are taking on the federal workforce.