Candida auris is a rising global health threat due to multidrug resistance, emphasizing the urgent need for novel antifungal strategies. The C. auris glycosylphosphatidylinositol transamidase (GPI-T) complex is the key enzyme that mediates the attachment of GPI anchors to target proteins.

Researchers have identified a critical genetic pathway involving the protein FOXO1 that maintains the health of the epididymis, a vital component of the male reproductive system. The study reveals that the age-related decline of this pathway drives cellular senescence and infertility. Furthermore, experimental treatments using specialized stem cells demonstrated the ability to restore this pathway, offering a promising new strategy for preserving male reproductive longevity.

A new clinical study shows that electroacupuncture (EA) can significantly improve long-term facial paralysis symptoms and help regulate brainstem excitability, even when using minimal stimulation that patients can barely feel.