Pressure-eyes at night: Researchers find new mechanism that causes increase in internal eye pressure, and a possible new target for glaucoma treatment
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Oct-2026 05:16 ET (25-Oct-2026 09:16 GMT/UTC)
One of the major risk factors for Glaucoma is an increase in intraocular pressure. Intraocular pressure fluctuates throughout the day and is known to rise at night, but the detailed molecular mechanisms on why this happens have not been fully understood. Kyushu University researchers found that norepinephrine raises levels of RHOB in the eye’s drainage system called the trabecular meshwork, leading to the eye’s ‘cleaning function’ weakening and increased intraocular pressure.
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