‘Supportive’ brain cells may drive cognitive decline, study finds
Peer-Reviewed Publication
Updates every hour. Last Updated: 24-Oct-2026 22:16 ET (25-Oct-2026 02:16 GMT/UTC)
Brain cells that produce the protective coating around nerve fibres can become dysfunctional with age and may actively contribute to cognitive decline, according to new research.
Electrochemical energy technologies are central to the net-zero transition, yet their multiscale characteristics ranging from atomic materials to device architectures present critical challenges in research and development (R&D). Although artificial intelligence (AI) has accelerated discovery and design in this field, commonly used predictive AI methods remain limited in enabling disruptive advances. Generative AI has shown transformative potential in disciplines such as biology and medicine, though its impact on electrochemical energy R&D is only beginning to emerge. Here we review recent progress in applying generative AI to molecular and crystal discovery, electrode microstructure design, and system optimization, with particular attention to the role of large language models in electrochemical engineering. We argue for a paradigm shift toward generative electrochemical intelligence (GenE), a physics-informed, multimodal framework that integrates human expertise with automated experimentation. We anticipate that GenE will redefine the R&D paradigm for rapidly deployable electrochemical energy technologies and accelerate their translation into real-world applications.
Research published in The Lancet Regional Health – Americas, based on nearly 30 million births, reveals that drought is associated with a greater likelihood of preterm birth and, when prolonged, impaired fetal growth. Concurrent drought and extreme heat further increase the risk of preterm birth, particularly among the most socioeconomically vulnerable populations. The study, scientifically coordinated by IR Sant Pau, will continue by examining the potential effects of drought on childhood growth through age five.
A multi-institutional research team from Fuzhou University, Huazhong University of Science and Technology, and collaborating institutions has published a comprehensive review on small-scale magnetic soft robots for medical applications. These miniature, soft robotic systems can be remotely actuated or manipulated by external magnetic fields, allowing operation in confined internal environments where conventional medical instruments may be difficult to miniaturize or maneuver. The review focuses on two major categories, untethered and tethered magnetic soft robots, and compares their development across five translational stages: basic performance testing, artificial model validation, ex vivo organ experiments, in vivo animal studies, and clinical translation. By examining technological progress, key milestones, clinical potential, and remaining barriers, the article provides a systematic roadmap for advancing magnetic soft robots from laboratory research toward safer and more standardized clinical use.
ζ-Carotene, a key intermediate in lycopene biosynthesis, is widely found in plants and photosynthetic microorganisms, but its isomer-specific properties remain poorly understood due to isolation and purification challenges. Researchers have now developed a purification strategy to obtain high-purity geometric isomers and systematically characterized, for the first time, their isomer-specific spectral properties, photoisomerization behavior, UV-shielding capacity, antioxidant activity, and skin-related biological activities—highlighting ζ-carotene's promise as a natural ingredient for skin health and photoprotection.
For the first time in Finland, population-level norm values have been established for estimating life expectancy adjusted for health-related functional capacity and productivity. The new study provides Finnish norm values for both everyday functioning and work ability, as well as for a newly developed measure, productivity-adjusted life expectancy.
Although experimental evidence supports links between exercise and certain mental health indicators, epidemiological research has focused primarily on the dose–response effect of a single type of exercise, overlooking potential differences across exercise types in their associations with overall and specific mental health outcomes.To examine the associations between different types of exercise and multiple mental health outcomes, including depression, anxiety, post-traumatic stress disorder, suicidal ideation, suicide attempts and nonsuicidal self-injury, and to explore their dose–response relationships in terms of exercise frequency and duration.