Most AI medical devices cleared for use were not tested on patient outcomes
Peer-Reviewed Publication
Updates every hour. Last Updated: 24-Oct-2026 22:16 ET (25-Oct-2026 02:16 GMT/UTC)
A new analysis shows that, of 1,357 artificial intelligence (AI)-based medical devices authorized by the U.S. Food and Drug Administration (FDA) for use in patient care, only three had been tested on whether they actually improve patients’ health. Rawan Abulibdeh of the University of Toronto, Canada, and colleagues present these findings in the open access journal PLOS Digital Health on August 19, 2026.
Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) have identified key social and environmental factors that influence how climate change affects childhood diarrheal diseases in sub-Saharan Africa. An August study published in Nature Communications found that while rising temperatures and changing rainfall patterns are likely to alter disease risks, factors such as vaccination, access to transportation, and other indicators of socioeconomic resilience can help reduce the impact of climate-related health threats. A second study that did an initial analysis of the data was published in the Journal of Infectious Diseases in June.
A newly published Viewpoint article in the journal BioScience argues that the contentious debate over the origins of SARS-CoV-2 could benefit from a well-established scientific approach for weighing competing explanations. Multiple working hypotheses and strong inference, argues author Alan B. Franklin (formerly of the USDA National Wildlife Research Center) could break the logjam of single-hypothesis reasoning that has marked the politically charged accusations that the SARS-CoV-2 originated from either an intentional or unintentional release from the Wuhan Institute of Virology versus from the proximate live animal market.
Large language models (LLMs), including the models behind ChatGPT and Claude as well as numerous other systems developed specifically for medical applications, are increasingly used in clinical workflows. They support medical documentation, summarize knowledge, and assist with clinical decision-making. However, their adoption is outpacing the development of systems for oversight and safety. An interdisciplinary team of researchers at the Else Kröner Fresenius Center (EKFZ) for Digital Health at TUD Dresden University of Technology and University Hospital Dresden, together with national and international colleagues, has systematically analyzed the risks associated with LLM use in medicine. The review, published in Nature, brings together evidence from medical AI, cybersecurity, regulatory science, ethics and behavioral psychology and outlines strategies for trustworthy and responsible use of artificial intelligence (AI) in clinical practice.
A recent study in the Journal of Nutrition Education and Behavior (JNEB), published by Elsevier, found that adolescents reported TikTok food content cued their desire to eat or try foods, while acknowledging that parents could play a protective role by helping them disengage from the platform and fostering critical conversations about food, bodies, influencers, and online health information. Participants frequently described TikTok food content as prompting hunger, cravings, and interest in trying new foods, while parental involvement could interrupt exposure to food-related content.
A new study from researchers at the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) has uncovered a previously unknown consequence of viral infection: too much RNA inside a cell can disrupt its ability to produce energy.
Published in the journal Proceedings of the National Academy of Sciences, the study found that when excess RNA builds up inside cells during poxvirus infection, it can impair mitochondria — the structures responsible for generating most of a cell’s energy — reducing the cell’s ability to function normally.
Researchers at the University of Osaka discovered that people who reach extreme old age have an unusual immune system. Around the age of 100, they develop large numbers of rare immune cells that resemble those seen in people fighting cancer, allowing them to remain highly active in their supercentenarian years. The findings suggest that the immune system can adapt with age and may help protect some people from disease to support exceptional longevity.