Living pharmacies use engineered cells to produce medicines inside the body. System integrates the cells with oxygen-producing bioelectronics in one wireless, fully implantable device. In animal studies, the device stably produced three different biologic drugs with three different half lives.

St. Jude Children’s Research Hospital scientists studied how prompting styles influence artificial intelligence’s ability to analyze interviews and identify childhood cancer survivors needing extra support.

Scientists at UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine developed BiliSeq, a molecular test that detected bile duct cancer with twice the sensitivity of the standard test, giving physicians a more accurate picture of the patient’s diagnosis.

Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor protein called TIE2 as the missing link between two key signaling pathways that drive the growth of blood vessel abnormalities known as cerebral cavernous malformations (CCMs). The study, to be published March 27 in the Journal of Experimental Medicine (JEM), suggest that drugs targeting TIE2 could be used to prevent the formation of CCMs, which, if left untreated, can cause brain hemorrhages, strokes, and seizures.