As the use of GLP-1 and other incretin-based medications for obesity continues to grow worldwide, researchers at Marshall University have contributed to an international effort to address one of medicine's most pressing unanswered questions: How should these medications be used by women before, during and after pregnancy?

About the Study: Can autonomous oxygen titration increase the proportion of time acutely ill adults receiving supplemental oxygen spend in a targeted normoxemia range (peripheral oxygen saturation 90%-96%) and decrease time spent in hypoxemia (peripheral oxygen saturation <88%)? In this randomized clinical trial among 300 acutely ill adults in 4 US hospitals, autonomous oxygen titration increased the proportion of time spent in normoxemia and decreased the proportion of time spent in hypoxemia compared to usual care. Autonomous oxygen titration safely increased the time that acutely ill adults spent in a targeted normoxemia range compared with oxygen delivery in current clinical care.

A University of Colorado Anschutz-led clinical trial has found an automated oxygen delivery system helped hospitalized patients spend significantly more time in their target oxygen range compared with standard care, while also reducing exposure to both low and high oxygen levels. Patients in the automated group spent 85 percent of their time in the target oxygen range compared with 63 percent in the standard care group.

New research from Oregon Health & Science University shows that millions of Medicaid-enrolled youth are now covered by managed care organizations owned by one of five national parent firms, and that behavioral health care patterns differ meaningfully depending on which firm a child’s plan belongs to.

Tissue-resident immune cells in the lungs can be dysfunctional and cause inflammation. Patients with autoimmune diseases such as lupus, rheumatoid arthritis, or scleroderma often have chronic lung inflammation.

UCLA researchers have identified a promising strategy to make a new class of targeted cancer therapies more effective against one of the deadliest forms of prostate cancer, potentially overcoming treatment resistance that has limited their success.

McGill University researchers have developed a new tool to identify heart disease risk in women earlier in life.

Findings from a study published in JACC: Advances highlight gaps in existing approaches.

“Heart disease is the leading cause of death in women, yet existing risk tools were developed in older populations and ignore factors unique to women,” said senior author Robert Platt, Professor in the Department of Epidemiology, Biostatistics, and Occupational Health and Director of the School of Population and Global Health.

While pregnancy complications are known to be linked to future heart risk, there has been no way to identify which younger women are most at risk, he added.