(Boston)—Throughout a person’s lifetime, the cells lining the respiratory tract are exposed to inhaled pollutants, including cigarette smoke. These exposures can cause molecular changes that disrupt normal cell behavior, leading to abnormal growth and function. Over time, these airway abnormalities—called bronchial premalignant lesions—can progress to a type of non-small cell lung cancer known as squamous cell carcinoma.

In a new study from Boston University Chobanian & Avedisian School of Medicine, researchers have identified a microRNA (miRNA)—a small non-coding RNA that can suppress gene expression—that is overexpressed in lesions that progress in severity. This miRNA reduces the expression of genes involved in immune recognition, potentially enabling abnormal cells to evade detection by the immune system.

The quality of a low-carbohydrate or low-fat diet may matter more than the amount of carbohydrates or fat consumed when it comes to reducing heart disease risk, according to a new study published in JACC, the flagship journal of the American College of Cardiology. Researchers found that versions of both diet patterns emphasizing macronutrients from healthy foods were associated with a lower risk of coronary heart disease (CHD), while versions high in refined carbohydrates and animal products were linked to higher risk and adverse metabolic profiles

Low-carbohydrate and low-fat diets rich in high-quality, plant-based foods and low in animal products and refined carbohydrates were linked with lower risk of heart disease, according to a new study led by researchers at Harvard T.H. Chan School of Public Health. The same diets that were rich in refined carbohydrates and high in animal fats and proteins were associated with a higher risk of heart disease. The study suggests that it’s the quality of the macronutrients composing these diets that make a difference for heart health, rather than the quantity.