10-Jun-2026
GLP-1s may alleviate depression in mice through the microbiome
Cell PressPeer-Reviewed Publication
Some people taking GLP-1 drugs for diabetes and obesity experience mental health benefits—particularly, a decrease in symptoms of depression. In a mouse model study in the Cell Press journal Cell Host & Microbe publishing on June 10, researchers report that these mental health improvements appear to result from changes in the gut microbiome that lead to an abundance of a microbe strain known to have a favorable effect on neurons related to stress.
- Journal
- Cell Host & Microbe
- Funder
- Ministry of Science and Technology of China, National Natural Science Foundation of Distinguished Young Scholars, National Natural Science Foundation of China, Ministry of Education of China, Major Science and Technology Projects in Jiangsu Province, Natural Science Foundation Outstanding Youth Fund of Jiangsu Province, Fundamental Research Funds for the Central Universities, Jiangsu Province High-Level Hospital Construction Funds of Zhongda Hospital, Southeast University, Nanjing U35 Strong Foundation Program