A brain rhythm working in tandem with the body’s natural sleep-wake cycle may explain why bipolar patients alternate between mania and depression, according to new research.

The McGill University-led study published in Science Advances marks a breakthrough in understanding what drives shifts between the two states, something that, according to lead author Kai-Florian Storch, is considered the “holy grail” of bipolar-disorder research.

Soybean growers across the globe face a silent but devastating threat: the soybean cyst nematode (SCN). This microscopic pathogen attacks soybean roots, jeopardizing crop yields and causing more than $1.5 billion in annual losses in the United States alone. Despite decades of effort, effective solutions to protect soybeans from SCN remain elusive, as the pathogen is often detected only in later stages because its early symptoms are subtle. However, new research offers hope for a sustainable solution to this agricultural challenge.

ProCure On-Demand’s 500th transplanted organ, being announced today, is emblematic of the gaps and inefficiencies in the current transplant system that the organ recovery, technology and logistics company is regularly solving. The transplant of the 500th organ underscores ProCure's reputation for efficient logistics and swift turnaround times, which have become integral to their success. With less than five hours to recover bilateral lungs, ProCure tapped into its unique Recovery Team Network, to deploy a surgeon to the donor hospital. Soon after, the lungs were on a 700-mile flight and transplanted into a recipient. Within a day of the transplant, the recipient of the gift of new lungs was breathing on their own and was able to get back home to continue healing within a few weeks. This case is the new paradigm in organ recovery that has been created and replicated by ProCure.