Scientists engineer first fully synthetic brain tissue model
Peer-Reviewed Publication
Updates every hour. Last Updated: 3-Apr-2026 08:15 ET (3-Apr-2026 12:15 GMT/UTC)
For the first time, scientists have grown functional, brain-like tissue without using any animal-derived materials or added biological coatings. The development opens the door to more controlled and humane neurological drug testing.
A team led by Cleveland Clinic’s Kenneth Merz, PhD, and IBM’s Antonio Mezzacapo, PhD, is developing quantum computing methods to simulate and study supramolecular processes that guide how entire molecules interact with each other.
In their study, published in Nature Communications Physics, researchers focused on molecules’ noncovalent interactions, especially hydrogen bonding and hydrophobic species. These interactions, which involve attraction and repulsive forces between molecules or parts of the same molecule, play an important role in protein folding, membrane assembly and cell signaling.
New research from Dartmouth reveals that artificial intelligence can now corrupt public opinion surveys at scale—passing every quality check, mimicking real humans, and manipulating results without leaving a trace. The findings, published in the Proceedings of the National Academy of Sciences, show just how vulnerable polling has become.
The gene editing tool known as CRISPR-Cas9 is changing what’s possible for treating a wide range of diseases caused by genetic mutations. But so far, attempts to use the technology to address brain-based genetic disorders have proved challenging in the lab. Scientists have now discovered why. In a study published in Nature Communications, researchers from Gladstone Institutes, the Innovative Genomics Institute, and UC Berkeley have shown that neurons and other nondividing cells respond differently to CRISPR-Cas9 gene editing than dividing cells.