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Updates every hour. Last Updated: 1-Apr-2026 17:16 ET (1-Apr-2026 21:16 GMT/UTC)
A roadmap for nanomedicine's 'long march': New review systematically charts path to brain
Tsinghua University PressTreating brain diseases like tumors and Alzheimer's is notoriously difficult due to the blood-brain barrier (BBB), which blocks most drugs. While nanomedicine offers a promising solution, its path to the brain is a complex, multi-stage journey fraught with obstacles. A new comprehensive review published in Nano Research provides a "roadmap" for this journey, systematically breaking down the entire process—from surviving in the bloodstream to crossing the BBB and precisely targeting diseased cells. By detailing the challenges at each step and highlighting innovative strategies to overcome them, this work serves as a crucial guide to accelerate the development of effective brain-targeted therapies.
- Journal
- Nano Research
TCM phenomics 2.0: The integration with digital medicine
China Association of Chinese Medicine, eTMAs an innovative integrated practice in the field of digital traditional Chinese medicine (TCM), TCM Phenomics 2.0 deeply integrates the core technologies and values of digital medicine. Leveraging cutting-edge technologies such as artificial intelligence and medical digital twins, it addresses the developmental bottlenecks of the first-generation TCM phenomics, and constructs a systematic closed-loop diagnosis and treatment system. It not only upgrades TCM diagnosis and treatment toward digitization and standardization, but also builds a pivotal bridge for the integration of TCM and Western medicine, pioneering an entirely new paradigm for the advancement of precision medicine.
- Journal
- Digital Chinese Medicine
Tinder and visual identity: a UOC study reveals the nine types of user profile photos
Universitat Oberta de Catalunya (UOC)Choosing a Tinder profile picture seems like a free, personal and creative act. But to what extent is that true? A new study developed by the Universitat Oberta de Catalunya (UOC) reveals that, far from being unique, most users opt for one of a very limited number of visual strategies. The research, conducted by Alejandro García Alamán, a member of the CIRCLE Lab and course instructor at the Faculty of Psychology and Education Sciences, identifies nine standardized types of profile that are systematically repeated on these kinds of platforms.
The study, based on an analysis of 1,000 real Tinder profiles in the Barcelona area, was published in The Journal of Sexual Medicine and combines psychological methods with data analysis and machine-learning techniques.
- Journal
- The Journal of Sexual Medicine
A shape-shifting scaffold that fights infection and rebuilds bone
Burns & Trauma- Journal
- Burns & Trauma
How lactate rewrites cartilage genes to attenuate post-traumatic osteoarthritis
Burns & Trauma- Journal
- Burns & Trauma
A 3D culture platform unlocks extracellular vesicle therapy for fibrotic skin repair
Burns & Trauma- Journal
- Burns & Trauma
Electroacupuncture calms neuronal stress to restore movement after spinal cord injury
Burns & Trauma- Journal
- Burns & Trauma
Jarzynski equality in the context of superconducting optical cavities: Classical limit and its connection with quantum resource theory
KeAi Communications Co., Ltd.This article investigates the classical limit of the Jarzynski equality in quantum systems, specifically using a nonlinear Jaynes-Cummings model representing a superconducting optical cavity with Kerr nonlinearity.
Key Findings:
Two Distinct Regimes: The study reveals a classical regime at high temperatures and low Kerr intensities where the Jarzynski equality holds, and a quantum regime at low temperatures and high Kerr intensities where it fails.
Quantum Resource Identification: The Kerr nonlinearity term creates quantum behavior that can be identified as a quantum resource for quantum computing advantages in non-zero temperature environments.
Work Operator Definition: The authors use a work operator in the interaction picture and apply Dyson expansion to evaluate the averaged exponentiated work.
Temperature-Nonlinearity Interplay: An intricate relationship between Kerr nonlinearity and temperature governs the quantum-to-classical transition and determines the validity domain of the Jarzynski equality.
Nonclassical Behavior: External work increases the state's nonclassicality, with deviations from Jarzynski equality serving as evidence of quantum behavior.
- Journal
- Quantum Review Letters
- Funder
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG), Brazil, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Brazil, National Council for Scientific and Technological Development (CNPq), Brazil
Powering forward: A year of discovery in mitochondrial science
KeAi Communications Co., Ltd.- Journal
- Mitochondrial Communications