A research team has uncovered how ethylene, a key plant hormone, enhances peanut seed germination by modulating hormonal pathways and promoting metabolic processes.

Inexpensive and easily available raw materials combined with practical and efficient preparation technology is an important direction for the future development of microwave absorption materials. In this study, coal tar pitch (CTP), an advantageous resource with low cost and wide source, be used as the carbon source. Hypercrosslinked porous polymers are prepared by crosslinking aromatic compounds in CTP based on the classical Friedel-Crafts reaction. Porous carbon (PC) microwave absorption materials will be prepared by high-temperature carbonization.

The study achieves efficient electrocatalysis for the electrooxidation reaction in multi-electrolyte systems by synergistically modulating structure and electronic coupling through rational design. The research team established novel principles for controlling the morphology and performance of MOFs: formation of nano-flower structure requires co-existence of Ni site and Fc ligand, doping of Fe sites promotes 3D crystal morphology development, which marks a pioneering advance in the field. Among them, the Bimetallic Dual-Ligand MOF: NFBF (6:2) exhibits outstanding electrocatalytic performance (210 mV at 10 mA·cm^-2). Operando Raman spectroscopy and XAFS reveal the electronic restructuring feature of NFBF (6:2) during the catalytic OER process. Combined with DFT calculations, which identify Ni as the catalytic active site, these investigations uncover significant electronic migration and redistribution, substantially reducing the reaction energy barrier and accelerating the catalytic process. Comprehensive exploration demonstrates that NFBF (6:2) not only performs well under various multi-electrolyte conditions but also maintains a nearly consistent catalytic mechanism. Furthermore, when applied to overall water splitting, (+) NFBF (6:2) | | NFBF (6:2) (-) achieves significant catalytic effects in both alkaline freshwater (1.40 V at 10 mA·cm^-2) and seawater (1.44 V at 10 mA· cm^-2) electrolyzers. This work highlights the crucial role of electronic coupling in optimizing electrocatalytic performance and offers new insights for addressing mitigating environmental pollution, embodying substantial practical and research potential.

Surface-engineered LNPs, propelled by clinical successes like patisiran and mRNA vaccines, enable targeted nucleic acid delivery via ligands (antibodies, peptides) and conjugation chemistries (click reactions). These LNPs target organs (liver, lungs) and cells (immune, brain), advancing gene therapy and vaccines. Key challenges—batch reproducibility, ligand stability, scalable production—must be resolved to accelerate clinical translation and expand applications to protein/small-molecule delivery.

This protocol establishes the chorioallantoic membrane (CAM) model in avian embryos to investigate migrasome-mediated angiogenesis mechanisms. Key methodologies include the CAM nylon mesh assay and ex vivo sprouting assay for quantifying vascular growth, alongside migrasome isolation, labeling, and targeted delivery. CRISPR-generated T4-KO-mCherry-KI embryos enable functional analysis of migrasome dynamics in real-time angiogenesis. The CAM's high vascularity and accessibility allow parallel assessment of pro-/anti-angiogenic factors and migrasome-cell interaction mapping. By integrating genetic editing and migrasome manipulation, this platform bridges migrasome biology with developmental angiogenesis, offering a scalable tool for mechanistic and therapeutic exploration.

This review focuses on the unique characteristics of mitochondrial nucleoids in mammalian cells, highlighting their semi-autonomous nature and the role of phase separation in their organization and function. It draws parallels to the well-established role of phase separation in nuclear architecture and gene regulation.

A scientific breakthrough at Tel Aviv University: A world-first study shows an acoustic interaction between plants and insects. In this study, the team focused on female moths and found that they make a critical decision—where to lay their eggs—based on sounds emitted by nearby plants. When plants emitted distress sounds, the female moths preferred healthy plants that were not emitting such sounds. These sounds are ultrasonic, beyond the hearing range of the human ear, but moths can hear them.

Morphine is a potent opioid medicine utilized for the management of moderate to severe pain, particularly in palliative care, post-surgical recovery, and cancer treatment. But, it carries risks of addiction liability and respiratory depression. Thus, aim of the review was designed to insights into morphine: extraction, structural characterization, and pharmacological properties. A literature survey on scientific journals, books as well as electronic sources was performed for the content. This review delves into the multifaceted aspects of morphine, one of the most well-known opiate analgesics, focusing on its extraction, structural characterization, and pharmacological properties. The pharmacological profile of morphine is critically examined, highlighting its mechanisms of action, including its interactions with opioid receptors, and the resulting physiological effects. Also, the therapeutic applications of morphine is discussed in pain management, its potential for addiction, and the emergence of tolerance. By synthesizing current knowledge, this review provides a comprehensive understanding of morphine’s significance in medicine and its implications for future pharmacological developments.

Dear Editor,

Nipah virus (NiV) poses a significant threat to global health security due to its high fatality rate and the possibility of human-to-human transmission.1 This zoonotic virus can cause serious effect in both animals and humans.2 Although there are currently no approved vaccines or therapeutics for NiV, there have been promising advances in vaccine development in recent years, bringing us one step closer to curbing the impact of this deadly disease. NiV outbreaks have been reported in several countries in southern Asian countries in support of their statement, outbreaks are taken place annually in Bangladesh.3 The main route of transmission to human is through contact with infected animals, particularly, flying fox (Pteropus) natural reservoir of the virus. However, raising concerns about the pandemic potential of the virus and their impact on human-to-human transmission has also been documented.4