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Updates every hour. Last Updated: 2-Apr-2026 12:16 ET (2-Apr-2026 16:16 GMT/UTC)
Facile-prepared FGF21/zinc nanocomplex for efficient brain delivery in ischemic stroke treatment
Tsinghua University PressProtein-based drugs demonstrate potent therapeutic effects but face rapid clearance from the body. To address this limitation for FGF21—a crucial neuroprotective protein with a short biological half-life—researchers developed an innovative zinc-based nanoformulation. The team successfully created FGF21/Zinc NC by combining FGF21 with zinc and stabilizing the complex with a PVP coating. This novel formulation demonstrated remarkable efficacy in stroke treatment, representing a significant breakthrough in overcoming a key obstacle for clinical development of protein therapeutics.
- Journal
- Nano Research
Virtual therapy strengthens social skills in autism
Graz University of Technology- Journal
- Scientific Reports
- Funder
- Austrian Science Fund
Ultrasonic sensor eliminates inspection blind spots in extreme environments
National Research Council of Science & Technology- Journal
- Mechanical Systems and Signal Processing
- Funder
- Ministry of Science and ICT
What are the highly concerned research topics in surface/interface science?
KeAi Communications Co., Ltd.Environmental Surfaces and Interfaces provides a platform for disseminating original and world-leading scientific research in the field. There is an emphasis on surface/interface science, including gas-liquid, liquid-liquid, gas-solid, liquid-solid, solid-solid and bio-interface. We welcome studies that advance basic theory, instrument and methodology development, and lab and field experimental research on environmental surfaces and interfaces.
- Journal
- Environmental Surfaces and Interfaces
Thymus function may hold the key to understanding immune ageing
Science Exploration PressResearchers from the Southern University of Science and Technology propose a “thymus-centric” framework to combat immunosenescence and improve health outcomes in older adults.
- Journal
- Ageing and Cancer Research & Treatment
- Funder
- Guangdong Science and Technology Program, Shenzhen Science and Technology Program, Shenzhen Science and Technology Program
Association between frailty, frailty domains, and health-related hope in patients with pre-dialysis chronic kidney disease
Osaka Metropolitan University- Journal
- Geriatric Nursing
Syngas production by photoreforming of formic acid with 2D VxW1−xN1.5 solid solution as an efficient cocatalyst
Shanghai Jiao Tong University Journal CenterFormic acid (FA) is a potential biomass resource of syngas with contents of carbon monoxide (CO, 60 wt.%) and hydrogen (H2, 4.4 wt.%). Among the technologies for FA conversion, the photoreforming of FA has received widespread attention due to its use of green solar energy conversion technology and mild reaction conditions. Herein, a V–W bimetallic solid solution, VxW1−xN1.5 with efficient co-catalytic properties was first and facilely synthesized. When CdS was used as a photocatalyst, the activity performance of the V0.1W0.9N1.5 system was over 60% higher than that of the W2N3 system. The computational simulations and experiments showed the V0.1W0.9N1.5 had great metallic features and large work functions, contributing a faster photo-generated carrier transfer and less recombination, finally facilitating a great performance in cocatalyst for syngas production in photoreforming FA. This work provides an approach to synthesizing novel transition metal nitrides for photocatalysis.
- Journal
- Frontiers in Energy
Navigating a year of climate turbulence: Researchers identify the top 10 global carbon neutrality events of 2025
Shanghai Jiao Tong University Journal CenterThe year 2025 witnessed several significant events with far-reaching impacts on carbon neutrality and the global climate change mitigation. The Research Institute of Carbon Neutrality at Shanghai Jiao Tong University has compiled and shared the “Top 10 Most Influential Events” in this field for 2025 to document the ambitious journey, sustained efforts, and collective footprints of humankind in addressing one of the greatest challenges our generation.
Inhalable self-assembled celastrol for acute bacterial pneumonia treatment
Tsinghua University PressMethicillin-resistant Staphylococcus aureus (MRSA) pneumonia is a well-recognized cause of bacterial pneumonia, resulting in increased morbidity and mortality worldwide. Traditional antibiotics face challenges such as resistance development and microbiome disruption. Researchers have now developed a promising alternative: chitosan-coated self-assembled celastrol nanoparticles (CSC NPs), derived from a traditional Chinese herbal compound. These CSC NPs, optimized for lung delivery via nebulization, exhibit strong mucoadhesion and acid-responsive drug release at infection sites. By non-competitively inhibiting the virulence factor staphyloxanthin (STX), CSC NPs disrupt bacterial membranes and enhance immune clearance. In mouse models, they achieved remarkable antibacterial rates of 97% against S. aureus and 94% against MRSA, offering a clinically translatable strategy to combat resistant infections.
- Journal
- Nano Research