Article Highlights
Updates every hour. Last Updated: 26-Jun-2025 13:10 ET (26-Jun-2025 17:10 GMT/UTC)
Biochar's benefits questioned: New review reveals flawed evidence
Maximum Academic Press- Journal
- Pedosphere
A hydrogen–deuterium exchange mass spectrometry-based protocol for protein-small molecule interaction analysis
Higher Education PressThis study establishes a standardized continuous-labeling, bottom-up hydrogen deuterium exchange mass spectrometry (HDX-MS) protocol to investigate conformational dynamics in protein–small molecule interactions, using the N-terminal domain of Hsp90 (Hsp90N) as a model system.
- Journal
- Biophysics Reports
- Funder
- National Key Research and Development Program of China, Shanghai Young Excellent Academic Leader Program, Shanghai Municipal Science and Technology Major Project, National Natural Science Foundation of China, Youth Innovation Promotion Association CAS
Isolation and proteomic study of fish liver lipid droplets
Higher Education PressThis study focuses on lipid droplets (LDs), which are organelles responsible for storing neutral lipids and are found across various species. The excessive accumulation of these lipids in LDs is linked to several metabolic disorders. Zebrafish, with their transparent embryos, present a valuable model for studying LD biology, though previous research has been hampered by the absence of specific LD marker proteins and limitations in purification techniques.
- Journal
- Biophysics Reports
- Funder
- National Key Research and Development Program of China, National Natural Science Foundation of China
Measurement of ATGL activity using adiposomes
Higher Education PressAdipose triacylglycerol lipase (ATGL) is a dynamic lipid droplet-associated protein involved in cellular lipolysis, which is conserved from bacteria to humans. Recent methods that measure the enzymatic activity of ATGL in vitro are established using lipid emulsions. However, the lipid emulsion platforms contain various membranous structures which reduce the accuracy of enzymatic activity determination. Therefore, a new platform and corresponding method are required for accurate measurement of ATGL enzymatic activity that represents cellular lipid and energy homeostasis. Adiposomes are artificial lipid nanostructures mimicking lipid droplets. Employing adiposome as a platform, the authors have developed an assay to measure the enzymatic activity of ATGL in vitro. Here, a detailed protocol is described to explain how to measure the activity of ATGL using adiposomes. This method successfully proves the concept of lipid droplet-mimetic lipase activity determining platform and provides a tool to identify the active sites of lipases.
- Journal
- Biophysics Reports
- Funder
- National Natural Science Foundation of China, National Key Research and Development Program of China
Research shows ‘it takes a village’ to address childhood anxiety and depression
Murdoch University- Funder
- Murdoch University, Western Australia Anxiety Disorders, Beyond Blue, Australian Research Council
FLAPS: Fluctuation-aware power auction strategy for reducing the power overload probability
Higher Education PressA team from EPCC proposed FLAPS, a fluctuation-aware power auction strategy to optimize data center power utilization. FLAPS reduces power overload by 9%–10% while maintaining high resource utilization.
- Journal
- Frontiers of Computer Science
New soil DNA monitoring technique provides data for better urban wildlife planning
Yale UniversityYale School of the Environment scientists pioneered a novel approach to studying the impact of urbanization on biodiversity in cities.Using eDNA, which captures genetic material shed by organisms into their surroundings, Yale School of the Environment scientists tracked how human disturbance is impacting mammal communities. The new research published in the Journal of Animal Ecology advances novel eDNA monitoring techniques that will help scientists and city officials better manage urban biodiversity and human-wildlife interactions.
- Journal
- Journal of Animal Ecology
- Funder
- U.S. National Science Foundation
Transverse thermoelectric generation with the world’s highest power density using new material "thermoelectric permanent magnet"
National Institute for Materials Science, Japan- Journal
- Energy & Environmental Science
- Funder
- Japan Science and Technology Agency
CO2 to protein: yeast surpasses traditional feeds in sustainability
Higher Education PressEdible yeast Candida utilis can produce high-quality protein using DHA with 60.1% protein content at rapid growth rates, supporting sustainable feed and food supply.
- Journal
- Systems Microbiology and Biomanufacturing
- Funder
- National Key Research and Development Program of China, National Natural Science Foundation of China, Yulin University and the Dalian National Laboratory for Clean Energy