In January 2026, the team led by Huang Wei, Zhao Chen and Lei Yiting from the First Affiliated Hospital of Chongqing Medical University, in collaboration with the team of João F. Mano from the University of Aveiro, published a review article in Research entitled "Metabolism-Regulating Microspheres: Design Principles, Therapeutic Applications Across Multisystem Diseases, and Future Perspectives".

Beryllium is valued for its light weight, strength, and heat resistance, making it important in aerospace, alloys, optics, and other advanced industries. But when beryllium enters wastewater during mining and processing, it can pose serious risks to ecosystems and human health. Long-term exposure to beryllium can damage the lungs and other organs, while beryllium-containing waste may threaten soil and water environments.

High-altitude environments, characterized by hypobaric hypoxia, intense ultraviolet radiation, and cold, are increasingly recognized as significant drivers of accelerated biological aging, posing complex public health challenges as human activity in these regions grows. While traditional views often focus on acute mountain sickness, emerging evidence from epidemiological, epigenetic, and microbiological studies reveals that prolonged exposure can decouple chronological age from biological age, leading to premature declines in cognitive, physical, and metabolic health. This commentary synthesizes recent research to argue that high-altitude living acts as a potent environmental stressor that accelerates the aging process through multiple interconnected pathways, albeit with notable paradoxes and dose-dependent effects that complicate a straightforward narrative.

Maternal mortality in Sierra Leone used to be among the highest in the world.  A 15-year-old non-profit programme that trains community health officers to do life-saving surgeries has helped slash that risk by two-thirds.  

This Perspective highlights how engineered chiral nanomaterials can regulate immune cells and reshape cancer therapy strategies. A multi-scale "Design-Validate-Translate" framework offers a roadmap for translating chirality from structural design to functional, clinically relevant nanomedicines.

A high-resolution cellular atlas of liver fibrosis and recovery identifies two proteins, SEMA4D and LMCD1, as promising therapeutic targets. The findings were validated in both mouse models and human patient samples, suggesting relevance to human disease.

A research team from the School of Public Health at the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has found that brisk interval walking performed once a week can significantly improve body fat reduction and cardiorespiratory fitness in adults with central obesity, comparable to exercising three times a week – the traditional recommendation for exercise frequency. The study provides strong scientific evidence supporting the therapeutic use of once-weekly brisk interval walking as a convenient exercise approach for adults with central obesity, particularly for those with time constraints. The findings were published in Nature Communications.